Linus P. Rweyemamu, Gokce Akan, Ismael C. Adolf, Erick P. Magorosa, Innocent J. Mosha, Nazima Dharsee, Lucy A. Namkinga, Sylvester L. Lyantagaye, Abdolrahman S. Nateri & Fatmahan Atalar
Background: Recent epidemiological studies suggest that reproductive factors are associated with breast cancer (BC) molecular subtypes. However, these associations have not been thoroughly studied in the African populations. The present study aimed to investigate the prevalence of BC molecular subtypes and assess their association with reproductive factors in Tanzanian BC patients.
Methods
This hospital-based case-only cross-sectional study consisted of 263 histologically confirmed BC patients in Tanzania. Clinico-pathological data, socio-demographic characteristics, anthropometric measurements, and reproductive risk factors were examined using the Chi-square test and one-way ANOVA. The association among reproductive factors and BC molecular subtypes was analyzed using multinomial logistic regression. The heterogeneity of the associations was assessed using the Wald test.
